ThinPrep Cytology for Cervical Carcinoma and Precancerous Lesion Screening:An Analysis of 55 221 Cases

Objective To investigate the relationship of the occurrence of cervical cancer and precancerous lesions to age by using ThinPrep cytology test(TCT) and Bethesda system(TBS).Methods A retrospective analysis was performed in 55 221 women who underwent TCT in gynecology clinic of the First Affiliated Hospital of Nanchang University from January 2006 to December 2011.Atypical squamous cells of undetermined significance(ASC-US) or above of the cases were positive cases.Results Among the 55 221 specimens,4 689(8.49%) were within normal limits(WNL),46 840(84.82%) were benign reactive changes(BCC),1 956(3.54%) were ASC,1 014(1.84%) were low grade squamous intraepithelical lesion(LSIL),450(0.81%) were high grade squamous intraepithelical lesion(HSIL),147(0.27%) were squamous cell carcinoma(SCC),103(0.19%) were atypical glandular cells of undetermined significance(AGC),and 22(0.04%) were adenocarcinoma(AC).Conclusion Cervical cancer and precancerous lesions tend to affect younger individuals.TCT can prevent the occurrence of cervical cancer and precancerous lesions.