Low dose misoprostol on induction of labor in term pregnancy

AIM: To determine the efficacy and safely of 33.3 μg misoprostol on induction of labor for term pregnancy. METHODS: Group misoprostol:31 women of term pregnancy with single pregnant, vertex present and intact membrane were selected in study group. Misoprostol of low dose (33.3 μg) was placed in posterior vaginal fornix every 4 to 6 hours to induce labor. Group oxytocin: 28 women of term pregnancy with same condition were selected, oxytocin of low dose (5% glucose sodium chloride injection 500 mL+2.5 IU oxytocin iv, drip) induced labor. RESULTS: The suscesessful rates of labor induction were 81% and 57% in group misoprostol and oxytocin, respectively. These were significant differences, P 0.05. The average durations from administration of misoprostol and oxytocin to the stat of labor in two groups were 14 h±13 h and 27 h± 16 h respectively. There were significant differences, P 0.05 . Duration of the stage of labor, mode of delivery and amount blood loss in postpartum were no significant differences, P 0.05 , between two groups. CONCLUSION: Low dose (33.3 μg) of misoprostol is an efficient and safe method for labor induction in term pregnancy. This mothod is better than oxytocin in sucesessful rates of labor induction and decrement of the time of labor induction.