Analysis on four serological test result before transfusion of the hospitalized patients and its clinical significance

Objective To discuss the clinical significance of four serological test result before transfusion from the hospitalized patients on hospital infection management and controlling,in order to do a good job of self-protection and prevention of cross infection,while avoiding the occurrence of medical disputes.Methods The serum hepatitis B surface antigen(HBsAg),human immunodeficiency virus(type Ⅰ,type Ⅱ) antibody(anti-HIV1 /2),hepatitis C antibody(anti-HCV),syphilis antibody(anti-TP) of 3 237 hospitalized patients before transfusion were tested by enzyme-linked immunosorbent assay(ELISA) from 2007 to 2010.Results The total positive samples were 531 cases,with total positive rate of 16.40%.362 cases were detected positive of HBsAg,and anti-HIV were found in 13 cases,50 cases were detected positive of anti-HCV,116 cases were anti-TP positive,confirmatory test by syphilis(TPHA) confirmed 106 cases.Inspection of the gender perspective,the anti-TP positive rate(4.16%) of male was higher than 2.52% of females,the difference was significantly different(P0.05).Conclusion The detection of four serological test in patients with serological before blood transfusion could help us to know the health status of patients,and avoid or reduce the medical disputes of blood transmitted diseases caused by blood transfusion.