Analysis of test results of infectious indexes in blood transfusion patients before transfusion

Objective To detect the infectious indexes in the blood transfusion patients before transfusion and to analyze the infection status of relative infectious diseases in order to reduce and avoid the transfusion-inducing medical disputes and medical personnel vocational infections.Methods 32 418 patients undergoing blood transfusion from January 2007 to September 2010 were detected for hepatitis B surface antigen(HBsAg)and human immunodeficiency virus antibody(anti-HIV1/2)by enzyme-linked immunosorbent assay(ELISA),and for hepatitis C virus antibody(anti-HCV)and syphilis antibody(anti-TP)by colloidal gold method.Results In the detected patients,4 863 positive specimen(15.0%)were found.Among them,there were 4 460 cases of HBsAg positive(13.9%),265 cases of anti-HCV positive(0.82%),401 cases of anti-TP positive(1.24%)and 67 cases of anti-HIV-positive(0.21%).Among HIV-positive specimens,different degrees of superinfection occurred,and HCV infection had the highest superinfection rate.In addition,the anti-TP positive rate increased significantly year by year,and the majority of infected people were the elderly over the age of 40.Conclusion Detection of infectious markers before blood transfusion is important to reduce the medical disputes,strengthen the self-protection awareness of medical staffs and reduce the risk of occupational exposure.