Effect of repaglinide on type 2 diabetes

Objective:To investigate the effects of repaglinide on type 2 diabetes and side effects of hypoglycemia.Methods:One hundred and twenty-four patients with type 2 diabetes were divided randomly into 3 groups,patients in group A were treated with repaglinide,patients in group B were treated with repaglinide and metformin,and patients in group C were treated with repaglinide and α glucosidase inhibitor;the therapy course was 12 weeks;effect of blood glucose control and side effects were observed and compared.Results:Avarage fasting blood glucose 2 hours postprandial blood glucose decrease in patients of group A,B and C were 23.5%,32.6% and 21.8%,32.5 % and 15.7%,29.8 % respectively.Conclusion:Repaglinide alone or combined with other medication can significantly lower fasting blood glucose and postprandial blood glucose of patients with type 2 diabetes,and no hypoglycemia and other serious adverse reactions occure.