Extraction and Inclusion Technology for Volatile oil from Wenweiyang Capsules

Objective To optimize the volatile oil extraction and inclusion process of Wenweiyang capsules.Methods An orthogonal test was adopted in this study. The extraction technology was optimized for the yield of volatile oil regarding the amount of water loaded,grain size of medicinal material,and decoction time as factors. The inclusion technology was optimized for the inclusion yield and volatile oil inclusion rate regarding the ratio of β-CD: oil,amount of water and grinding time as factors. Results The optimized extraction parameters were as follows: breaking medicinal material through 10 mesh screen,adding 6 fold volume of water and extracting for 5 h. The optimized inclusion progress was grinding at the β-CD : oil ratio of 8∶ 1,loading equivalent amount of water and grinding for 30 minutes. The average yield of volatile oil is 1. 72%,the average inclusion rate is 93. 01% and the average volatile oil inclusion rate is 74. 82%. Conclusion The extraction and inclusion technology is simple,reliable,which can effectively retain the volatile oil and provide evidence for the preparation of Wenweiyang capsules.