Optimization of Extraction and Inclusion Technology for Volatile Oil from Anti-rheumatism Capsules

Objective:To optimize extraction and inclusion technology of volatile oil from anti-rheumatism capsules.Method:Volatile oil was extracted by steam distillation method,with yield of volatile oil as index,effect of water amount and extraction time on extraction technology was investigated by single factor test;Volatile oil was inclused by saturated aqueous solution method using inclusion ratio as index,orthogonal test was used to optimize inclusion technology with ratio of volatile oil to β-cyclodextrin,inclusion time and temperature as factors.Result:Optimum extraction conditions were:extracted 4 h with 14 times the amount of water;Optimal inclusion technology was as followings:ratio of volatile oil to β-cyclodextrin 1∶ 8,inclusion tempemture 40 ℃,inclusion time 3 h.Conclusion:These optimized extraction and inclusion technology conditions were reasonable and feasible.