2002•Hebei yixueRequires access

Prevent and treat the cerebral vasospasm after subarachnoid hemorrhage with low dosage of Nimodipine

You-Lan Wang

Abstract

Objective:To study the therapeutic effect of low dosage of Nimodipine on the cerebral vasospasm(CVS) after subarachnoid hemorrhage (SAH).Method:39 cases by using Nimodipine and 21 cases in control group.The patients in Nimodipine group were transfused 4～10mg Nimodipine per day for 2～3 weeks.After that were changed to oral with 20～40mg 3/d for another 1-2 weeks(total 4 weeks).The control group was only treated in regular way for 4 weeks.Results:The incident and lethality rates of CVS after SAH in Nimodipine group were significantly lower than those in SAH control group (P0.05 and P0.001).Conclusion:low dosage of Nimodipine has significant therapeutic effect to prevent and treat cerebral vasospasm after SAH.

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Key concepts: Nimodipine, Medicine, Subarachnoid hemorrhage, Cerebral vasospasm, Anesthesia, Vasospasm, Therapeutic effect, Surgery