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Effect of Nimodipine for 120 patients with subarachnoid hemorrhage

Bing Liu

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Abstract

Objective To explore the effect of Nimodipine in the treatment of subarachnoid hemorrhage(SAH).Method Total 120 cases with SAH were randomly divided into two groups,60 cases in each group.The treatment group was given continuous pumped-in Nimodipine plus oral medication,the control group with conventional therapy,and the effects was compared between the two groups.Results The cure rate in the treatment group was significantly higher than the control group,and the difference was significant(P0.01).The cerebral vasospasm(CVS) rate in the treatment group was lower than the control group,and showed significant difference(P0.01).The incidence of rehaemorrhagia and mortality between the two groups showed no significant difference(P0.05).Conclusion Nimodipine can significantly reduce the incidence of CVS after SAH and doesn't increase the risk of rehaemorrhagia,but can not reduce the mortality after SAH.

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What this paper is about

Objective To explore the effect of Nimodipine in the treatment of subarachnoid hemorrhage(SAH).Method Total 120 cases with SAH were randomly divided into two groups,60 cases in each group.The treatment group was given continuous pumped-in Nimodipine plus oral medication,the control group with conventional therapy,and the effects was compared between the two groups.Results The cure rate in the treatment group was significantly higher than the control group,and the difference was significant(P0.01).The cerebral vasospasm(CVS) rate in the treatment group was lower than the control group,and showed significant difference(P0.01).The incidence of rehaemorrhagia and mortality between the two groups showed no significant difference(P0.05).Conclusion Nimodipine can significantly reduce the incidence of CVS after SAH and doesn't increase the risk of rehaemorrhagia,but can not reduce the mortality after SAH.

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Available abstract

Objective To explore the effect of Nimodipine in the treatment of subarachnoid hemorrhage(SAH).Method Total 120 cases with SAH were randomly divided into two groups,60 cases in each group.The treatment group was given continuous pumped-in Nimodipine plus oral medication,the control group with conventional therapy,and the effects was compared between the two groups.Results The cure rate in the treatment group was significantly higher than the control group,and the difference was significant(P0.01).The cerebral vasospasm(CVS) rate in the treatment group was lower than the control group,and showed significant difference(P0.01).The incidence of rehaemorrhagia and mortality between the two groups showed no significant difference(P0.05).Conclusion Nimodipine can significantly reduce the incidence of CVS after SAH and doesn't increase the risk of rehaemorrhagia,but can not reduce the mortality after SAH.

Key concepts: Nimodipine, Medicine, Subarachnoid hemorrhage, Anesthesia, Cerebral vasospasm, Incidence (geometry), Significant difference, Vasospasm

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