Use of Brain Natriuretic Peptide and C-Reactive Protein in Acute Myocardial Infarction

Objective To study the value of brain natriuretic peptide( BNP) and C-reactive pro- tein( CRP) in acute myocardial infarction. Methods The levels of BNP and CRP were measured in 126 patients with AMI and 40 healthy controls. The difference was compared between two groups. The mortality and the risks of major adverse cardiac events( including the composite end point of death,recurrent myocardial infarction,angina pectoris,heart failure,and re-hospitalization) at 28 d were analyzed. The correlation of BNP and CRP levels with MACE was compared. Results The levels of BNP and CRP in AMI group were significantly higher than control group( P 0. 01) . The levels of BNP and CRP in AMI patients of MACE group were significantly higher than those in non-MACE group ( P 0.01) . Conclusion The levels of BNP and CRP had a certain clinical significance on diagno- sis,prognosis and assessment of AMI patients.