The relationship of BNP,hs-CRP with cardiac function in patients with acute myocardial infarction

Objective To investigate the plassma levels of brain natriuretic peptide(BNP) and high-sensitivity C-reactive protein(hs-CRP) in patients with acute myocardial infarction(AMI),and estimate its value in the risk stratification.Methods The BNP and the serum levels of hs-CRP were detected in 128 cases with non-AMI and 120 cases with AMI.Left ventricular ejection fraction(LVEF) and left ventilator posterior wall thickness growing rate at systole(△T%) were measured by echocardiography.Results Compared with control group,AMI patients had high serum levels of hs-CRP.The higher the killip class was,the higher the levels of hs-CRP and BNP were.The concentration BNP and hs-CRP in AMI patients had a parallel rationship with LVEDD(P 0.05),but a nenative correlation with left ventricular ejection fraction(LVEF)(P 0.05).Conclusion The concentration of BNP and hs-CRP can help to evaluate the risk stratification and prognosis in patients with AMI.