Correlation of metabolic syndrome with abdominal obesity in adolescents

Objective:To investigate the correlation of serum blood pressure, serum lipid, fasting glucose, 2-h postprandial glucose, fasting insulin and uric acid with abdominal obesity in adolescents. Methods: Altogether 174 high-school students (101 male, 73 female, age range: 17-21 years) were selected from Yangpu District of Shanghai and studied in the body mass index (BMI), waist circumference, blood pressure, serum lipid, fasting glucose, 2h postprandial glucose, fasting insulin and uric acid. Based on BMI and waist circumference, the subjects were divided into Group A (normal weight), B (non-abdominal obesity) and C (abdominal obesity). Results: Compared with Group A, increased SBP, DBP, TG, HDL-C, LDL-C, FINS, HOMA-IR and Ua were observed in Groups B and C, and significantly increased FPG and 2 h PG were noted in Group C (P 0.05). SBP, DBP, 2 h PG, FINS, TG, BMI and WC were markedly higher in Group C than in B (P 0.01). WC was more correlated with FPG, TG, HDL-C, LDL-C and Ua, but less correlated with 2 h PG, FINS, SBP and DBP than BMI. Conclusion: Adolescents with abdominal obesity have a higher risk of metabolic syndrome (MS) than those with non-adonimal obesity. The distribution of adipose tissues is correlated more with serum lipid (except TC), FPG and Ua than with BMI.