Omeprazole vs ranitidine in treating peptic ulcer with acute massive bleeding

Sixty-four patients with peptic ulcer with acute massive bleeding were equally divided into two groups.The omeprazole group(M26,F6;age 46±s 17 a) received omeprazole 40 mg,iv,q12 h,for 3d.The ranitidine group(M 25,F 7;age 47±16 a) received ranitidine 100 mg in 5% glucose solution 100mL, iv gtt,q 12 h, for 3-5d.They all aceepted routine antipeptic ulcer therapy after bleeding stopped.Definitive hemostasis was achieved in all the former group,but failed in 6 patients in the latter group(P0.05).The former group needed less days of hospitalization(P0.01),and less days of turning stool occult blood tests to negative(P0.01)in comparison with the latter group.