Therapeutic effect of PGE-1 combined with mecobalamin treatment for 58 patients with diabetic peripheral neuropathy

Objective To study the clinical therapeutic effect of PGE-1 combined with mecobalamin on diabetic peripheral neuropathy.Methods 108 patients with diabetic peripheral neuropathy in our department from February 2008 to December 2011 were divided into two groups randomly.In addition to control blood glucose,50 cases were treated with mecobalamin(control group),58 cases were treated with PGE-1 combined with mecobalamin on the basis of the treatment of control group(treatment group).The clinical effect and nerve conduction velocity of the two groups were compared.Results After treatment,the total effective rate of treatment group(89.65%)was significantly higher than that of control group(72%,P0.05);The motor nerve conduction velocity and sensory nerve conduction velocity of median nerve and peroneal nerve in treatment group were significantly higher than those in control group(P0.01).Conclusion PGE-1 combined with mecobalamin can be used to improve the nerve conduction velocity and clinical efficiency,it is worthy of clinical application.