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The significance of detection on cysteine C and NAG in diagnosis of early diabetic nephropathy

Yanfei Li

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Abstract

Objective To explore the significance of detecting cysteine C(Cys-c) and N-acetyl-β-D-glucosaminidase(NAG)in diagnosis of early diabetic nephropathy.Methods The Cys-c,Cr,BUN and NAG indexes of 62 cases of diabetes(including 35 cases of fasting blood glucose 7.8 mmol/L patients as poorly controlled glycaemic group,and 27 cases of fasting blood glucose≤7.8 mmol/L patients as well controlled glycemic group) were detected.Meanwhile 65 healthy people were selected randomly as the control group.Results The Cys-c and NAG of diabetic group were significantly increased compared with the control group(P0.01).The Cys-c and NAG in the well-controlled group were significantly lower than those in the poorly controlled group(P0.01).Conclusion The combined detection of Cys-c and NAG in patients with early diabetic nephropathy has important diagnostic value.

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Objective To explore the significance of detecting cysteine C(Cys-c) and N-acetyl-β-D-glucosaminidase(NAG)in diagnosis of early diabetic nephropathy.Methods The Cys-c,Cr,BUN and NAG indexes of 62 cases of diabetes(including 35 cases of fasting blood glucose 7.8 mmol/L patients as poorly controlled glycaemic group,and 27 cases of fasting blood glucose≤7.8 mmol/L patients as well controlled glycemic group) were detected.Meanwhile 65 healthy people were selected randomly as the control group.Results The Cys-c and NAG of diabetic group were significantly increased compared with the control group(P0.01).The Cys-c and NAG in the well-controlled group were significantly lower than those in the poorly controlled group(P0.01).Conclusion The combined detection of Cys-c and NAG in patients with early diabetic nephropathy has important diagnostic value.

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Available abstract

Objective To explore the significance of detecting cysteine C(Cys-c) and N-acetyl-β-D-glucosaminidase(NAG)in diagnosis of early diabetic nephropathy.Methods The Cys-c,Cr,BUN and NAG indexes of 62 cases of diabetes(including 35 cases of fasting blood glucose 7.8 mmol/L patients as poorly controlled glycaemic group,and 27 cases of fasting blood glucose≤7.8 mmol/L patients as well controlled glycemic group) were detected.Meanwhile 65 healthy people were selected randomly as the control group.Results The Cys-c and NAG of diabetic group were significantly increased compared with the control group(P0.01).The Cys-c and NAG in the well-controlled group were significantly lower than those in the poorly controlled group(P0.01).Conclusion The combined detection of Cys-c and NAG in patients with early diabetic nephropathy has important diagnostic value.

Key concepts: Diabetic nephropathy, Glycemic, Diabetes mellitus, Medicine, Internal medicine, Gastroenterology, Nephropathy, Clinical significance

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