Effectiveness of Clinical Pharmacists ' Intervention on Prophylactic Use of Antibiotics for Surgical Patients undergoing Type I Incision Surgery

OBJECTIVE: To evaluate the role and effectiveness of clinical pharmacists ' intervention on the prophylactic use of antibiotics in surgical patients undergoing type Ⅰ incision surgery in Hechi Donglan County People's Hospital. METHODS: 205 discharged surgical cases from May 2010 to April 2011( before intervention) were assigned to non-intervention group and 251 discharged surgical cases collected during stage Ⅰ( from May 2011 to April 2012) vs. 263 discharged surgical cases collected during stage Ⅱ( from May 2012 to April 2013) were assignedto intervention group. The rationality in the prophylactic use of antibiotics in surgical patients undergoing type Ⅰ incision surgery before and after intervention was compared. RESULTS: After stage Ⅰ intervention,the proportion of patients administered with antibiotics reduced from 100%( before intervention) to 99. 6%( after intervention) and the course of treatment was reduced from 5-14 days before intervention( an average of 8. 39 days,with discharge medication of oral antibiotics) to 1-8 days( an average of 2. 8 days); antibiotics were not used in 1 case; the proportion of patients administered with antibiotics for ≤24 hours for 25-48 hours showed sharp increase from 0%; the proportion of patients administered with antibiotics for ≤24 hours has reached 40. 64%; the proportion of patients administered with antibiotics for 3-7 days or 7 days showed a sharp decrease; the drug choice,administration time, intraoperaitve medication,dosage administration became more and more rational,and drug combination and routes of administration were completely rational. After stage Ⅱ intervention,the proportion of patients administered with antibiotics reduced from 100%( before intervention) to 5. 70%( after intervention) and even the patients with medication indications had no prophylactic use of antibiotics in the later stage; the course of treatment was 0-1 day( an average of 0. 057 days),and all the other antibiotic use indicators were rational with grade A healing of incision( without infection). CONCLUSION: Clinical pharmacists' intervention on the prophylactic use of antibiotics in surgical patients undergoing type Ⅰ incision surgery achieved noticeable effectiveness and met the requirement of special rectification activities in 2012 on clinical application of antibacterial drugs'.