ScholarLens Back to search
2008•Lishizhen Medicine and Materia Medica ResearchRequires access

The Effects of Semen Ziziphi Spinosae Decoction on Sleeping State in Rats

LI Ting-li

Open publisher page 1 citations

Abstract

Objective To study the effects of Semen ziziphi spinosae decoction on sleeping states.Methods Polysomnography was used to record the changes of EEG and EMG in rats in different sleeping states,and the influences of Semen ziziphi spionsae decoction on them were observed.Results After intragastric administration with Semen ziziphi spinosae decoction(17.5 g/kg crude drug) for 7 days,TST and SWS2 were increased in free-moving rats,but SWS1and REMS had no significant changes.Conclusion The decoction of Semen ziziphi spinosae can prolong TST of rats,selectively increase SWS2 and has no obvious changes in REMS,indicating it has few side-effects.

About this research paper

What this paper is about

Objective To study the effects of Semen ziziphi spinosae decoction on sleeping states.Methods Polysomnography was used to record the changes of EEG and EMG in rats in different sleeping states,and the influences of Semen ziziphi spionsae decoction on them were observed.Results After intragastric administration with Semen ziziphi spinosae decoction(17.5 g/kg crude drug) for 7 days,TST and SWS2 were increased in free-moving rats,but SWS1and REMS had no significant changes.Conclusion The decoction of Semen ziziphi spinosae can prolong TST of rats,selectively increase SWS2 and has no obvious changes in REMS,indicating it has few side-effects.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To study the effects of Semen ziziphi spinosae decoction on sleeping states.Methods Polysomnography was used to record the changes of EEG and EMG in rats in different sleeping states,and the influences of Semen ziziphi spionsae decoction on them were observed.Results After intragastric administration with Semen ziziphi spinosae decoction(17.5 g/kg crude drug) for 7 days,TST and SWS2 were increased in free-moving rats,but SWS1and REMS had no significant changes.Conclusion The decoction of Semen ziziphi spinosae can prolong TST of rats,selectively increase SWS2 and has no obvious changes in REMS,indicating it has few side-effects.

Key concepts: Decoction, Semen, Medicine, Traditional medicine, Pharmacology, Andrology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The Effects of Semen Ziziphi Spinosae Decoction on Sleeping State in Rats — Research Paper | ScholarLens