Clinical Curative Effect of High-dose Thermo-lipiodol Embolization in Treatment of Huge Hepatocellular Carcinoma

Objective To study the curative effect of high-dose thermo-lipiodol embolization for treatment of huge hepatocellular carcinoma.Methods 216 patients with huge hepatocellular carcinoma were divided into A and B groups.Group A(heating group) was given with transcatheter arterial high-dose thermo-lipiodol embolization,and Group B(control group) with transcatheter arterial high-dose thermo-lipiodol embolization under normal temperature.All of the patients should be diagnosed as hepatocellular carcinoma by B-ultrasonography,CT,MRI and AFP in advance,with a nidus diameter between 11 and 19cm and iodipin consumption between 15 and 40mL.The lessened focus,survival time and AFP changes were evaluated.Results There were significant differences between Group A and B(P 0.05).36-month follow-up was performed.The survival rate of Group A was 96.42%,83.04%,72.32%,51.79% or 33.93% respectively at the 6th,12th,18th,24th and 36th month,and the corresponding number was 108,93,81,58 or 38.The survival rate of Group B was 82.69%,68.27%,58.65%,41.35% or 13.46% respectively at the 6th,12th,18th,24th and 36th month,and the corresponding number was 86,71,61,43 or 14.Conclusion The effect of High-dose thermo-lipiodol embolization in treatment of huge hepatocellular is better than that under normal temperature.