Transcatheter Arterial Chemo Embolization Combined with ~(131)I Lipiodol for the Treatment of Primary Hepatocellular Carcinoma

Objective To study the therapeutic effect of transcatheter arterial chemoembolization(TACE) combined with iodine 131 Lipiodol( 131 I Lipiodol) for primary hepatocellular carcinoma(PHC).Methods 68 patients with PHC were divided into two groups.In group A,34 patients were treated by TACE,and in group B,34 patients treated by TACE combined with 131 I Lipiodol.Results In group A, second stage surgical resection rate was 8.8%,histologic examination of cancer specimens obtained from hepatectomy showed that TACE could not cause complete necrosis.The 1 ,2 ,and 3 year survival rate of the treated cases was 64.3%, 39.3% and 21.4%,respectively.In contrast,in group B,the second stage surgical resection rate was 29.4%,combination therapy resulted in complete histologic necrosis in 76.9% of patients.The 1 ,2 ,and 3 year survival rate was 96.4%,82.1% and 60.7%,respectively.Conclusion The therapeutic effect of TACE combined with 131 I Lipiodol is much better than that of TACE alone.