The clinical study on interventional thermochemotherapy and embolization treatment of the advanced patients with hepatocellular carcinoma

Objective To evaluate the efficacy and side effects of interventional thermochemotherapy and embolization treatment of the advanced patients with hepatocellular carcinoma.Methods One hundred patients of advanced hepatocellular carcinoma were randomly divided into hyperthermia group and ordinary group,each group had 50 cases.All patients received transcatheter arteria chemoembolization,chemothrapy with ADM,MMC,5-Fu,CDDP,and super-liquid iodided oil was used.The tumor growth rate were recorded and all patients were followed up by examinations of AFP,ALT and AST.Results The tumor growth rate of hyperthermia group and ordinary group were(-8.56±28.42%),(10.25±43.3)%,respectively.There was significant statistial difference between the two groups(P0.05).There were significant statistical differences in level of AFP before and after procedure in the hyperthermia group and in the survival rate for 0.5,1,1.5,2 years between the two groups(P0.05),but there were no significant statistical differences in the level of positive ALT and AST and side effects between the two groups(P0.05).Conclusion The interventional thermochemotherapy and embolization treatment can effectively prolonged survival of the advanced patients with hepatocellular carcinoma.