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2013•China Practical MedicineRequires access

homocysteine, uric acid,in coronary heart disease

Ying-cheng Wagn

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Abstract

Objective To detect the levels of plasma serum levels of homocysteine(Hcy),uric acid(UA) and the correlation of the patients with coronary heart disease(CHD).Methods 100 patients with CHD were divided into acute myocardial infarction(AMI) group(n=50),USAP group(n=50),stable angina pectoris(SAP) group(n=30),and healthy control group(n=20) subjects matched for age,gender.The levels of plasma Hcy were measured with enzyme-linked immunosorbent assay(ELISA).UA were measured with uricase colorimetric assay.ResultsThe levels of Hcy,UA in patients with CHD were significantly higher than those in control group(P0.05).The levels of Hcy,UA in ACS group were significantly higher than those in SAP group(P0.05).There was significant difference between the AMI and USAP groups(P0.05).The correlation between Hcy and UA level was positive in CHD.Conclusion There is a significant correlation between Hcy,UA and the risk level of coronary heart disease.These two indexs can evaluate the severity dergee.

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What this paper is about

Objective To detect the levels of plasma serum levels of homocysteine(Hcy),uric acid(UA) and the correlation of the patients with coronary heart disease(CHD).Methods 100 patients with CHD were divided into acute myocardial infarction(AMI) group(n=50),USAP group(n=50),stable angina pectoris(SAP) group(n=30),and healthy control group(n=20) subjects matched for age,gender.The levels of plasma Hcy were measured with enzyme-linked immunosorbent assay(ELISA).UA were measured with uricase colorimetric assay.ResultsThe levels of Hcy,UA in patients with CHD were significantly higher than those in control group(P0.05).The levels of Hcy,UA in ACS group were significantly higher than those in SAP group(P0.05).There was significant difference between the AMI and USAP groups(P0.05).The correlation between Hcy and UA level was positive in CHD.Conclusion There is a significant correlation between Hcy,UA and the risk level of coronary heart disease.These two indexs can evaluate the severity dergee.

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Available abstract

Objective To detect the levels of plasma serum levels of homocysteine(Hcy),uric acid(UA) and the correlation of the patients with coronary heart disease(CHD).Methods 100 patients with CHD were divided into acute myocardial infarction(AMI) group(n=50),USAP group(n=50),stable angina pectoris(SAP) group(n=30),and healthy control group(n=20) subjects matched for age,gender.The levels of plasma Hcy were measured with enzyme-linked immunosorbent assay(ELISA).UA were measured with uricase colorimetric assay.ResultsThe levels of Hcy,UA in patients with CHD were significantly higher than those in control group(P0.05).The levels of Hcy,UA in ACS group were significantly higher than those in SAP group(P0.05).There was significant difference between the AMI and USAP groups(P0.05).The correlation between Hcy and UA level was positive in CHD.Conclusion There is a significant correlation between Hcy,UA and the risk level of coronary heart disease.These two indexs can evaluate the severity dergee.

Key concepts: Medicine, Homocysteine, Internal medicine, Uric acid, Myocardial infarction, Unstable angina, Coronary heart disease, Cardiology

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