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The Relation Between nm23,LN-R and Lymph Node Metastasis of Cholangiocarcinomas

Da Li

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Abstract

Objective Study the correlation of the expression of nm23\|H1 and LN\|R with the biologic behavior and lymph node metastasis in the cholangiocarcinomas.Methods Using S\|P immunohistochemical methods.Results There were significant differences among different histopathological types and degrees of differentation of nm23\|H1 and LN\|R (P0.05) .nm23\|H1 low expression tumours were associated with a higher incidence of metastasis to lymph nodes than were nm23\|H1 normal expressive (P0.05) .The metastatic rate of tumours stained positively for LN\|R were higher than in those with negative LN\|R staining (P0.05) .Conclusion It is suggested that nm23\|H1 low\|expression and LN\|R overexpression might play signficant role in lymph node metastasis in the cholangiocarcinomas.

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Objective Study the correlation of the expression of nm23\|H1 and LN\|R with the biologic behavior and lymph node metastasis in the cholangiocarcinomas.Methods Using S\|P immunohistochemical methods.Results There were significant differences among different histopathological types and degrees of differentation of nm23\|H1 and LN\|R (P0.05) .nm23\|H1 low expression tumours were associated with a higher incidence of metastasis to lymph nodes than were nm23\|H1 normal expressive (P0.05) .The metastatic rate of tumours stained positively for LN\|R were higher than in those with negative LN\|R staining (P0.05) .Conclusion It is suggested that nm23\|H1 low\|expression and LN\|R overexpression might play signficant role in lymph node metastasis in the cholangiocarcinomas.

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Available abstract

Objective Study the correlation of the expression of nm23\|H1 and LN\|R with the biologic behavior and lymph node metastasis in the cholangiocarcinomas.Methods Using S\|P immunohistochemical methods.Results There were significant differences among different histopathological types and degrees of differentation of nm23\|H1 and LN\|R (P0.05) .nm23\|H1 low expression tumours were associated with a higher incidence of metastasis to lymph nodes than were nm23\|H1 normal expressive (P0.05) .The metastatic rate of tumours stained positively for LN\|R were higher than in those with negative LN\|R staining (P0.05) .Conclusion It is suggested that nm23\|H1 low\|expression and LN\|R overexpression might play signficant role in lymph node metastasis in the cholangiocarcinomas.

Key concepts: Immunohistochemistry, Lymph node metastasis, Lymph, Metastasis, Lymph node, Pathology, Medicine, Incidence (geometry)

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