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Optimization of Extraction Process for Acid-Soluble Collagen fromCyprinus carpioHaematopterus Scale by Response Surface Methodology

Zhu Wen-xu

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Abstract

On the basis of one-factor-at-a-time experiments,Box-Behnken design(BBD) and response surface methodology(RSM) were applied to explore the effects of acetic acid concentration,material/liquid ratio and extraction duration on the extraction efficiency of collagen from common carp fish scale.As a result,a mathematical model was fitted.The optimal extraction conditions were found to be 0.54 mol/L acetic acid as the extraction solvent with a material/liquid ratio of 1:10(g/mL) for an extraction duration of 42 h.Under these conditions,the extraction efficiency of collagen was 15.89%.

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What this paper is about

On the basis of one-factor-at-a-time experiments,Box-Behnken design(BBD) and response surface methodology(RSM) were applied to explore the effects of acetic acid concentration,material/liquid ratio and extraction duration on the extraction efficiency of collagen from common carp fish scale.As a result,a mathematical model was fitted.The optimal extraction conditions were found to be 0.54 mol/L acetic acid as the extraction solvent with a material/liquid ratio of 1:10(g/mL) for an extraction duration of 42 h.Under these conditions,the extraction efficiency of collagen was 15.89%.

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Available abstract

On the basis of one-factor-at-a-time experiments,Box-Behnken design(BBD) and response surface methodology(RSM) were applied to explore the effects of acetic acid concentration,material/liquid ratio and extraction duration on the extraction efficiency of collagen from common carp fish scale.As a result,a mathematical model was fitted.The optimal extraction conditions were found to be 0.54 mol/L acetic acid as the extraction solvent with a material/liquid ratio of 1:10(g/mL) for an extraction duration of 42 h.Under these conditions,the extraction efficiency of collagen was 15.89%.

Key concepts: Response surface methodology, Extraction (chemistry), Acetic acid, Chromatography, Box–Behnken design, Solvent, Chemistry, Materials science

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Optimization of Extraction Process for Acid-Soluble Collagen fromCyprinus carpioHaematopterus Scale by Response Surface Methodology — Research Paper | ScholarLens