The clinical study of compound azintamide combined with mosapride in the treatment of slow transit constipation

Objective To observe the curative effect of compound azintamide combined with mosapride in the treatment of slow transit constipation(STC). Methods 450 patients with STC were randomly divided into treatment group A, control group B,and control group C.295 patients completed,compound azintamide combined with mosapride was provided to the treatment group A(n=113);only compound azintamide was given to the control group B(n=98);only mosapride was supplied to the control group C(n=84).After 3-month treatment,the effects were observed. Results The total effective rate in group A,group B,and group C was 89.4%,66.3%,and 70.2% respectively,the group A was superior to that of both group B and group C(P0.01),there was no significant difference between group B and group C( P0.05). Conclusion The effect of compound azintamide combined with mosapride in the treatment of STC is more remarkable than that only compound azintamide or only mosapride treatment.It can obviously alleviate the relative symptoms of STC like abdominal distension,which is worthy of expansion in clinic and normative study further.