Comparison of curative effects of combined usage of mosapride and hydrotclcire for the treatment of patients with bile reflux gastritis

Objective To comparison the curative effects and safety of combined usage of mosapride combined with hydrotalcite or azintamide for the treatment of patients with bile reflux gastritis(RBG).Methods A total of 128cases of RBG patients were randomly divided into group A(64cases),given mosapride combined with hydrotalcite and group B(64cases),given mosapride combined with azintamide,respectively.The treatment course was 4 weeks.Clinical effect,change of symptom scores and side effect were compared.Results The effective rate in group A was 89.1%,significantly higher than the 75.0%in group B(P0.05).After treatment,the symptom scores of nausea,vomiting,abdominal pain and abdominal distension in the two groups were significantly lower than those before treatment(P0.05),and these indicators in group A were decreased more significantly than those in group B(P0.05).The incidence rates of side effect in group A and group B were 9.4% and 12.5%,without statistical difference(P0.05).Conclusion Mosapride combined with hydrotalcite could be with better curative effects than mosapride combined with azintamide for treatment of RBG.