Effect of indapamide on the treatment isolatedsystolic hypertension in elderly patients

Objective:To discuss the effects of indapamide on the treatment isolated systolic hypertension (ISH) in elderly patients.Methods:One hundred and two patients ISH of elderly were recuited and divided into group indapamide (n=52,indapamide 1.25 ～ 2.5 mg/d)and group felodipine(n=50,felopdipine 5～15 mg/d).Siting blood pressure was measured by the every 1～2 weeks.Fasting blood glucose, blood lipid,blood creatinine, uric acid, blood potassium,blood natrium and blood chlorine, were examined before and after 2 months treatment.Results:Comparing with before treatment, the blood pressure in both groups decreased significanthy, but not difference between 2 groups. The levels of blood glucose, blood lipids, creatinine and potassium didn't change after treatment.Conclusion:Indapamid is a safer drug for elderty patients with systolic hypertension.