2010•Chinese Journal of Birth Health & HeredityRequires access
Analysis on karyotype of villus tissue cells from 107 missed abortion fetus
Zhu Jian-jiang
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Abstract
Objective:To investigate the relationships between abnormal karyotypes of fetal chorionic villus cells and missed abortion.Methods:107 samples of fetal villus tissue cells were detected by the conventional G-banding chromosome analysis after uterine curettage.Results:There were 64 cases of abnormal karyotypes in total 107 samples,abnormal rate achieve 59.8 %.Of which,58 cases were chromosome number abnormality,5 cases were chromosomal structural abnormality.Conclusion:The chromosomal abnormality is an important reason for missed abortion.Chromosome analysis of fetal villus tissue cells can provide reliable evidence for etiological diagnosis and next reproductive counselling.