Clinical observation on bronchiolitis treated with intravenous drip of ambroxol

Objective: To explore the therapeutic effect and safety of bronchiolitis treated with intravenous drip of ambroxol. Methods: 126 hospitalized cases with bronchiolitis from January to December 2006 were selected as control group,and 124 hosptalized cases with bronchiolitis from January to December 2007 were selected as treatment group,the cases in the two groups were treated with anti-infection,hormone,spasmolysis and relieving cough,aspiration of sputum if necessary,the severe cases were treated with oxygen uptake and vasoactive drugs; the cases with heart failure were treated with cedilanid and furosemide,based on the treatment mentioned above, the cases in treatment group were treated with intravenous drip of ambroxol for 5 ～ 7 days,2 mg·kg -1,twice a day. The disappearance times of symptoms and signs,hospitalization time of the two groups and adverse reactions of treatment group were compared. Results: The therapeutic effects of treatment group were superior to those of control group in terms of improving wheezes symptom,removing pulmonary wheeze and rale,shortening hospitalization time and obvious effective rate. Conclusion: The therapeutic effect of intravenous drip of ambroxol is satisfactory in treatment of bronchiolitis,no obvious adverse reactions are found and the method is worth popularizing.