ScholarLens Back to search
2006•The Journal of Clinical PsychiatryRequires access

Antipsychotics combined with lithium in the treatment of acute mania

Liu Chong-min

Open publisher page 0 citations

Abstract

Objective:To compare the efficacy and safety of risperidone,clozapine and chlopiomazine combined with lithium in acute mania respectively. Method:All patients with acute mania according to CCMD- 3 were randomly assigned to receive risperidone,clozapine or chlopiomazine respectively and all of them combined with lithium.The study lasted for 8 weeks.The efficacy and safety were evaluated with mania rating scale (MRS) and treatment emergant symptom scale (TESS) respectively. Results:The efficacy of resperidone group was similar to the other groups and had less side effects.Resperidone group took effect more slowly than clozapine group,but was similar to chlopromazine group. Conclusion:The efficacy and safety of risperidone combined with lithium are higher in acute mania.It may be a good choice in the treatment of acute mania.

About this research paper

What this paper is about

Objective:To compare the efficacy and safety of risperidone,clozapine and chlopiomazine combined with lithium in acute mania respectively. Method:All patients with acute mania according to CCMD- 3 were randomly assigned to receive risperidone,clozapine or chlopiomazine respectively and all of them combined with lithium.The study lasted for 8 weeks.The efficacy and safety were evaluated with mania rating scale (MRS) and treatment emergant symptom scale (TESS) respectively. Results:The efficacy of resperidone group was similar to the other groups and had less side effects.Resperidone group took effect more slowly than clozapine group,but was similar to chlopromazine group. Conclusion:The efficacy and safety of risperidone combined with lithium are higher in acute mania.It may be a good choice in the treatment of acute mania.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To compare the efficacy and safety of risperidone,clozapine and chlopiomazine combined with lithium in acute mania respectively. Method:All patients with acute mania according to CCMD- 3 were randomly assigned to receive risperidone,clozapine or chlopiomazine respectively and all of them combined with lithium.The study lasted for 8 weeks.The efficacy and safety were evaluated with mania rating scale (MRS) and treatment emergant symptom scale (TESS) respectively. Results:The efficacy of resperidone group was similar to the other groups and had less side effects.Resperidone group took effect more slowly than clozapine group,but was similar to chlopromazine group. Conclusion:The efficacy and safety of risperidone combined with lithium are higher in acute mania.It may be a good choice in the treatment of acute mania.

Key concepts: Mania, Risperidone, Lithium (medication), Clozapine, Young Mania Rating Scale, Medicine, Psychiatry, Rating scale

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Antipsychotics combined with lithium in the treatment of acute mania — Research Paper | ScholarLens