2011•Medical Journal of National Defending Forces in Northwest ChinaRequires access
Diagnostic value of combined detection of AFP,CEA and CA199 in primary liver cancers
Feng Zhang
Open publisher page 0 citations
Abstract
Objective: To study the clinical value of combined detection of the serum levels of AFP,CEA and CA199 in primary liver cancers.Methods: Collecting the serum samples from 110 primary hepatic cancer patients and 152 benign liver disease patients(hepatic cirrhosis and chronic hepatitis),the serum levels of AFP,CEA and CA199 were measured by chemiluminescence.Results: The levels of AFP,CEA and CA199 were(60.6 ± 80.5) μg/L,(22.2 ±13.9) μg/L and(47.2 ±28.3) U/L in primary liver cancer patients respectively,it was significantly higher than that in benign liver disease patients.The serum positive ratio of AFP,CEA and CA199 in primary liver cancer patients were 74.6%,49.1% and 45.6%,respectively,it was significantly higher than that in benign liver disease patients too.The sensitivity of combined detection of three kinds of tumor markers was 92.7%.Conclusion: The combined detection of AFP,CEA and CA199 can arise the diagnosis sensitivity of primary hepat-ic cancer,it has some value in screening primary hepatic cancers.