2010•Hainan yixueRequires access

Subarachnoid-epidural analgesia with different doses of sufentanil combined with ropivacaine during labor.

WU Zhao-xi

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Abstract

Objective To study the efficacy and safety of subarachnoid-epidural analgesia with different doses of sufentanil combined with ropivacaine during labor.Methods Sixty patients were received intrathecal sulfentanil 3μg,5μg,7μg and 2 mg ropivacaine randomly.An epidural catheter was then placed for patient-controlled epidural analgesia(PCEA).The onset and duration of subarachnoid analgesia,VAS scores,local anesthetic dose,motor block,birth process time,1,5min Apgar scores of neonates and adverse reactions of patients were recorded respectively.Results Good analgesic effects were obtained in all three analgesic groups.In group 5μg and group 7μg,the onset of analgesia were faster,the anesthetic duration of first dosage was longer,the total dose of ropivacaine was lower,and motor block case was less compare with group 3μg(P 0.05),but there was no significant difference in above index between group 5μg and group 7μg.There were no statistic differences in the duration of labor process,Apgar scores of neonates.The rate of obstetric forceps and the rate of caesarean section of patients were low and no statistic differences.Conclusion Subarachnoid analgesia(sufentanil 3,5,7μg + ropivacaine 2mg) can offer safety and efficacy of labor analgesia.Intrathecal sufentanil 5μg and ropivacaine 2mg is the best combination for labor analgesia.

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Objective To study the efficacy and safety of subarachnoid-epidural analgesia with different doses of sufentanil combined with ropivacaine during labor.Methods Sixty patients were received intrathecal sulfentanil 3μg,5μg,7μg and 2 mg ropivacaine randomly.An epidural catheter was then placed for patient-controlled epidural analgesia(PCEA).The onset and duration of subarachnoid analgesia,VAS scores,local anesthetic dose,motor block,birth process time,1,5min Apgar scores of neonates and adverse reactions of patients were recorded respectively.Results Good analgesic effects were obtained in all three analgesic groups.In group 5μg and group 7μg,the onset of analgesia were faster,the anesthetic duration of first dosage was longer,the total dose of ropivacaine was lower,and motor block case was less compare with group 3μg(P 0.05),but there was no significant difference in above index between group 5μg and group 7μg.There were no statistic differences in the duration of labor process,Apgar scores of neonates.The rate of obstetric forceps and the rate of caesarean section of patients were low and no statistic differences.Conclusion Subarachnoid analgesia(sufentanil 3,5,7μg + ropivacaine 2mg) can offer safety and efficacy of labor analgesia.Intrathecal sufentanil 5μg and ropivacaine 2mg is the best combination for labor analgesia.

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Available abstract

Objective To study the efficacy and safety of subarachnoid-epidural analgesia with different doses of sufentanil combined with ropivacaine during labor.Methods Sixty patients were received intrathecal sulfentanil 3μg,5μg,7μg and 2 mg ropivacaine randomly.An epidural catheter was then placed for patient-controlled epidural analgesia(PCEA).The onset and duration of subarachnoid analgesia,VAS scores,local anesthetic dose,motor block,birth process time,1,5min Apgar scores of neonates and adverse reactions of patients were recorded respectively.Results Good analgesic effects were obtained in all three analgesic groups.In group 5μg and group 7μg,the onset of analgesia were faster,the anesthetic duration of first dosage was longer,the total dose of ropivacaine was lower,and motor block case was less compare with group 3μg(P 0.05),but there was no significant difference in above index between group 5μg and group 7μg.There were no statistic differences in the duration of labor process,Apgar scores of neonates.The rate of obstetric forceps and the rate of caesarean section of patients were low and no statistic differences.Conclusion Subarachnoid analgesia(sufentanil 3,5,7μg + ropivacaine 2mg) can offer safety and efficacy of labor analgesia.Intrathecal sufentanil 5μg and ropivacaine 2mg is the best combination for labor analgesia.

Key concepts: Ropivacaine, Medicine, Sufentanil, Anesthesia, Apgar score, Analgesic, Caesarean section, Local anesthetic

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Subarachnoid-epidural analgesia with different doses of sufentanil combined with ropivacaine during labor. — Research Paper | ScholarLens