Clinical Study of Labor Analgesia R by Ropicavaine combined with Sufentanil for Subarachnoid Injection

Objective To study the efficacy and safety of subarachnoid Space analgesia with different doses of ropivacaine combined with sufentanil during labor.Methods 240 cases of single cephalic primiparas were randomly divided into three groups(n=80):eighty patients were received intrathecal ropivacaine 1.50 mg,1.75 mg,2.00 mg and 5 μg sufentanil in L2-3 row.An epidural catheter was then placed for patient-controlled epidural analgesia(PCEA).The onset and duration of ropivacaine analgesia,VAS scores,local anesthetic dose motor block,birth process time,Mode of delivery,Use of prenatal contractions,Across the stage of continuous fetal heart monitor,uterine contractions and blood pressure,blood oxygen saturation,1,5,10 min Apgar scores of neonates and adverse reactions of patients were recorded respectively.Results Good analgesic effects were obtained in all three analgesic groups.In group 1.75 mg and group 2.00 mg,the onset of analgesia were faster,the anesthetic duration of first dosage was longer,the total dose of ropivacaine was lower,and motor block case was less compare with group 1.50 mg(P0.05),group 2.00 mg prenatal contractions of vaginal instrumental delivery rate,prime rate was higher than the group 1.50 mg,1.75 mg(P0.05).But there was no significant difference in above index between group 1.75 mg and group 2.00 mg.There were no statistic differences in the duration of labor process,Apgar scores of neonates.Conclusion Subarachnoid analgesia(ropivacaine 1.50,1.75,2.00 mg+sufentanil 5 μg) can offer safety and efficacy of labor analgesia.Intrathecal ropivacaine 1.75 mg and sufentanil 5 μg was the best combination for labor analgesia.