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2010•Heilongjiang Medical JournalRequires access

The Relation Between the Expression of nm23-H1,PCNA and the Metastasis of Cervical Carcinoma

Ren Sheng

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Abstract

Objective To study the expression of nm23-H1 and PCNA in the metastasis of cervical carcinoma.Methods The expression of nm23-H1,PCNA in 47 cases cervical carcinoma was studied with SP immunohistochemcal technique.Results In cervical carcinoma,the positive nm23-H1 and PCNA,were 51.06%and 65.96%.The nm23-H1 in squamous cell carcinoma was 43.3%,adenocarcinoma was 64.7%.The positive in squamous cell carcinoma without metasis of lymph node was 62.5%(10/16),metastasis of lymph node was 21.4%(3/14)(P0.001).The nm23-H1 expression level was inversely correlated with lymph node in squamous cell carcinoma.Conclusion The expression of nm23-H1 and PCNA may be the reliable indicators to judge the prognosis of cervical carcinoma.

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Objective To study the expression of nm23-H1 and PCNA in the metastasis of cervical carcinoma.Methods The expression of nm23-H1,PCNA in 47 cases cervical carcinoma was studied with SP immunohistochemcal technique.Results In cervical carcinoma,the positive nm23-H1 and PCNA,were 51.06%and 65.96%.The nm23-H1 in squamous cell carcinoma was 43.3%,adenocarcinoma was 64.7%.The positive in squamous cell carcinoma without metasis of lymph node was 62.5%(10/16),metastasis of lymph node was 21.4%(3/14)(P0.001).The nm23-H1 expression level was inversely correlated with lymph node in squamous cell carcinoma.Conclusion The expression of nm23-H1 and PCNA may be the reliable indicators to judge the prognosis of cervical carcinoma.

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Available abstract

Objective To study the expression of nm23-H1 and PCNA in the metastasis of cervical carcinoma.Methods The expression of nm23-H1,PCNA in 47 cases cervical carcinoma was studied with SP immunohistochemcal technique.Results In cervical carcinoma,the positive nm23-H1 and PCNA,were 51.06%and 65.96%.The nm23-H1 in squamous cell carcinoma was 43.3%,adenocarcinoma was 64.7%.The positive in squamous cell carcinoma without metasis of lymph node was 62.5%(10/16),metastasis of lymph node was 21.4%(3/14)(P0.001).The nm23-H1 expression level was inversely correlated with lymph node in squamous cell carcinoma.Conclusion The expression of nm23-H1 and PCNA may be the reliable indicators to judge the prognosis of cervical carcinoma.

Key concepts: Medicine, Proliferating cell nuclear antigen, Lymph node metastasis, Carcinoma, Metastasis, Cervical carcinoma, Lymph node, Adenocarcinoma

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