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2014•Tianjin Journal of Traditional Chinese MedicineRequires access

Therapeutic effect of modified Liangxue Xiaofeng decoction and effect on peripheral interleukin-8 in patients with psoriasis with blood heat syndrome

Yanqi Xie

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Abstract

[Objective] To explore the therapeutic mechanism of modified Liangxue Xiaofeng decoction and the effect on interleukin-8(IL-8) of peripheral blood in patients with psoriasis with blood heat syndrome. [Methods] The level of IL-8 before and after treatment by modified of Liangxue Xiaofeng decoction for 8 weeks was measured in patients by ELISA methods. [Results] IL-8 of peripheral blood were higher in patients than that in controls(P0.01). After treatment, IL-8 of peripheral blood and the PASI were lower than that before(P0.01). [Conclusion] The modified of Liangxue Xiaofeng decoction may reduce psoriatic symptoms by reducing the activation of complement and inhibiting the inflammation reaction.

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What this paper is about

[Objective] To explore the therapeutic mechanism of modified Liangxue Xiaofeng decoction and the effect on interleukin-8(IL-8) of peripheral blood in patients with psoriasis with blood heat syndrome. [Methods] The level of IL-8 before and after treatment by modified of Liangxue Xiaofeng decoction for 8 weeks was measured in patients by ELISA methods. [Results] IL-8 of peripheral blood were higher in patients than that in controls(P0.01). After treatment, IL-8 of peripheral blood and the PASI were lower than that before(P0.01). [Conclusion] The modified of Liangxue Xiaofeng decoction may reduce psoriatic symptoms by reducing the activation of complement and inhibiting the inflammation reaction.

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Available abstract

[Objective] To explore the therapeutic mechanism of modified Liangxue Xiaofeng decoction and the effect on interleukin-8(IL-8) of peripheral blood in patients with psoriasis with blood heat syndrome. [Methods] The level of IL-8 before and after treatment by modified of Liangxue Xiaofeng decoction for 8 weeks was measured in patients by ELISA methods. [Results] IL-8 of peripheral blood were higher in patients than that in controls(P0.01). After treatment, IL-8 of peripheral blood and the PASI were lower than that before(P0.01). [Conclusion] The modified of Liangxue Xiaofeng decoction may reduce psoriatic symptoms by reducing the activation of complement and inhibiting the inflammation reaction.

Key concepts: Decoction, Medicine, Psoriasis, Peripheral blood, Peripheral, Therapeutic effect, Gastroenterology, Internal medicine

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Therapeutic effect of modified Liangxue Xiaofeng decoction and effect on peripheral interleukin-8 in patients with psoriasis with blood heat syndrome — Research Paper | ScholarLens