Prevalence of vascular diseases and their factors relatedto impaired glucose tolerance in elderly male subjects

Objective To study the prevalence of vascular diseases and their factors related to impaired glucose tolerance(IGT) in elderly male subjects. Methods A total of 141 IGT patients aged above 60 years were included. Besides them 73 subjects with normal glucose tolerance (NGT group) and 79 newly diagnosed diabetic (DM group) patients were also studied. BMI, blood pressure, blood glucose and lipid levels were compared among the three groups and the risk factors of IGT were analyzed. Results Compared with NGT group, the prevalence of hypertension and cerebrovascular diseases was significantly higher in IGT group. In IGT group, the prevalence of hypertriglyceridemia and elevated UAE was higher than that in NGT one and lower than that in DM one. Both UAE≥10μg/min and hypertriglyceridemia were the risk factors for developing IGT in elderly male subjects by multivariate regression analysis. Conclusions ① Much more elderly males with IGT suffered from hypertension and cerebrovascular diseases as compared with NGT group. Incidence of hypertriglyceridemia and elevated UAE was high in elderly male IGT subjects. ② Both elevated UAE and hypertriglyceridemia were risk factors for developing IGT in elderly male subjects. ③ Elevated UAE , hypertriglyceridemia and hypertension were the risk factors for DM in elderly male subjects.