The other cardiovascular risk factors and their clustering in elderly persons of impaired glucose tolerance

Objective: To investigate the cardiovascular risk factor and their clustering in elderly persons of impaired glucose tolerance. Method: According to 83 g oral glucose tolerance test(OGTT),131 eldly subjects were divided into normal glucose tolerance(NGT) group, impaired glucose tolerance(IGT) group,to compare the cardiovascular risk factors and their clustering, and the disease incidence of cardiovascular event . Result: (1)The levels of triglyceride were higher, HDL cholesterol were lower markedly(P 0.05 ) in subjects with IGT than those in NGT, compared with NGT group, the mean values of systolic blood pressure,diastolic blood pressure, body mass index were significantly higher in those with IGT( P 0.01 ). (2)Compared with NGT group,the proportion in subjects with IGT who concurrent hypertension, obesity, disturbances of lipid metabolism and ≥cardiovascular risk factor(2RFs) were significantly higher (P0.01). (3)The disease incidence of cardiovascular event in subjects with IGT who company with ≥2RFs were obviously higher than NGT( P0.05). Conclusion: There are significantly risk of incident of CVD in subjects with IGT, IGT is an independent risk factor of CVD. The phenomenon of clustering of cardiovascular risk factors was found in IGT, the disease incident of CVD were obviously increased. Thus, the patients with IGT should be intervened actively.