Relationship between liver function and serum lipid among patients with fatty live

Objective To investigate the characteristics of liver function and serum lipid among patients with fatty liver and to explore the relationship between them.Methods Liver function and serum lipid of 225 patients with fatty liver were compared with those of 187 normal controls,and the correlation between liver fuction and serum lipid was analyzed with Pearson analysis.Results The alanine aminotransferase(ALT)(49.49±42.87 U/L),aspartate aminotransferase(AST)(29.88±15.08 U/L),total cholesterol(TC)(5.06±0.92 mmol/L),triglyceride(TG)(1.96±1.44 mmol/L),and low density lipoprotein cholesterol(LDL-c)(3.33±0.74 mmol/L) of the fatty liver group were significantly higher than those of the control group.While AST/ALT(0.76±0.40) and high-density lipoprotein cholesterol(HDL-c)(1.30±0.25 mmol/L) were significantly lower(P0.005).Correlation analysis showed that in the fatty liver group,TC was positively correlated with total protein(TP) and albumin(ALB);TG was positively correlated with AST,TP,ALB,GLB;LDL-c was positively correlated with AST/ALT.Conclusion Liver function and serum lipid characters of the patients with fatty liver present the increased levels of ALT and AST within the normal reference range and abnormalities in serum lipid index.Some indicators of liver function relate closely to serum lipids,especially TC and TG.