Correlation between severe fatty liver and dyslipidemia

Objective:To investigate the correlation between severity of fatty liver disease and dyslipidemia.Methods:Selected 200patients with fatty liver as fatty liver group including 44mild cases,102 moderate cases,and 54severe cases,100cases without obvious abnormality were selected as control group.Blood lipid concentrations were detected in both groups.Results:Total cholesterol(TC),triglycerides(TG),high-density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C) of the fatty liver group were(5.57±1.38)mmol/L,(3.13±2.18)mmol/L,(0.92±0.26)mmol/L,(3.71± 0.93)mmol/L,respectively.And the corresponding levels in the control group were(4.24±0.75)mmol/ L,(1.34±0.82)mmol/L,(1.21±0.28)mmol/L,(2.19±0.78)mmol/L,showing significant differences between the two groups(Pall0.05).The above mentioned levels in the mild cases,moderate cases and severe cases were(4.98±0.95)mmol/L,(1.43±0.99)mmol/L,(1.15±0.26)mmol/L,(2.43±0.80) mmol/L,vs.(5.63±1.14)mmol/L,(2.32±1.81)mmol/L,(1.06±0.25)mmol/L,(3.15±0.91)mmol/L, vs.(6.14±1.56)mmol/L,(3.48±2.35)mmol/L,(0.87±0.28)mmol/L,(3.82±0.94)mmol/L,showing significant differences among patients with different severity(P0.05).Unconditioned Logistic multifactor regression analysis results showed that the TG is independent risk factors of fatty liver disease(P0. 05),the correlation analysis showed severity of fatty liver disease were positively correlated with TC,TG, LDL-C levels.(P0.05),and a weak negative correlation between HDL-C concentration and the disease severity was aloes observed(P0.05).Conclusion:Fatty liver disease is closely correlated with severity and abnormal blood lipid levels.