Diagnosis and Treatment of Pregnancy with Hyperthyroidism

Objective To explore the diagnosis and treatment of hyperthyroidism in the pregnant women to improve maternal and infant healthy. Methods 47 cases of pregnant women with hyperthyroidism were divided into the treatment group receiving anti-thyroid drug PTU and the non-treatment group, and 30 cases of normal pregnant women served as control. The levels of serum T 3, T 4, TSH, FT 3 and FT 4 were measured before delivery, and the neonatal thyroid functions were evaluated by detecting the levels of T 3,T 4 and TSH of umbilical blood, as well as peripheral blood at 3th, 5th and 7th days after birth. Results The levels of T 3,T 4, TSH,FT 3 and FT 4 in the non-treatment group were significantly higher than those in the treatment group and control group(P0 01), the neonatal body weight in the non-treatment group was significantly lower than those in the treatment group and control group, and the dystocia rate in the prognant women with hyperthroidism was much higher than that in normal pregnant women. There were 2 cases of infants with hyperthyroidism in the non-treatment group, and 3 cases of infants with hypothyroidism in the treatment group. Conclusion Pregnancy with hyperthyroidism should be diagnosed and treated as early as possible, and the delivery fashion should be paid more attention. Pregnancy with hyperthyroidism of post-treatment still had some effects on the outcome of infants, so thyroid function in fetus and infants should be examined strictly.