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2010•Zhongguo xin yao zazhiRequires access

Effects of flavones from Zea Mays L(ZMLF) on blood lipid and hemorheologic parameters in hyperlipemic rats

Tianhui Hu

Open publisher page 2 citations

Abstract

Objective:To explore the effects of flavones from Zea Mays L(ZMLF) on blood lipid and hemorheology in hyperlipidemic rats.Methods:Sixty Wistar rats were randomly divided into 5 groups;they fed with normal diet,or high fat diet to induce hyperlipidemia.ZMLF was administered for 40 days,then serum lipid and hemorrheologic indexes were measured.Results:The levels of TC,TG,LDL-C and apoB100 decreased significantly(P0.05),and those of HDL-C,apoAI and apoAI/apoB100 ratio increased(P0.05).The contents of the high,middle and low blood viscosity,plasma adhesion,hematocrit(HCT),RBC rigid index(IER),RBC aggregation index(IEA) decreased significantly(P0.05);while RBC deformation index(IED) increased significantly(P0.05).Conclusion:ZMLF can prevent high-fat diet-induced lipid metabolism disorders and the abnormal hemorheology.

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What this paper is about

Objective:To explore the effects of flavones from Zea Mays L(ZMLF) on blood lipid and hemorheology in hyperlipidemic rats.Methods:Sixty Wistar rats were randomly divided into 5 groups;they fed with normal diet,or high fat diet to induce hyperlipidemia.ZMLF was administered for 40 days,then serum lipid and hemorrheologic indexes were measured.Results:The levels of TC,TG,LDL-C and apoB100 decreased significantly(P0.05),and those of HDL-C,apoAI and apoAI/apoB100 ratio increased(P0.05).The contents of the high,middle and low blood viscosity,plasma adhesion,hematocrit(HCT),RBC rigid index(IER),RBC aggregation index(IEA) decreased significantly(P0.05);while RBC deformation index(IED) increased significantly(P0.05).Conclusion:ZMLF can prevent high-fat diet-induced lipid metabolism disorders and the abnormal hemorheology.

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Available abstract

Objective:To explore the effects of flavones from Zea Mays L(ZMLF) on blood lipid and hemorheology in hyperlipidemic rats.Methods:Sixty Wistar rats were randomly divided into 5 groups;they fed with normal diet,or high fat diet to induce hyperlipidemia.ZMLF was administered for 40 days,then serum lipid and hemorrheologic indexes were measured.Results:The levels of TC,TG,LDL-C and apoB100 decreased significantly(P0.05),and those of HDL-C,apoAI and apoAI/apoB100 ratio increased(P0.05).The contents of the high,middle and low blood viscosity,plasma adhesion,hematocrit(HCT),RBC rigid index(IER),RBC aggregation index(IEA) decreased significantly(P0.05);while RBC deformation index(IED) increased significantly(P0.05).Conclusion:ZMLF can prevent high-fat diet-induced lipid metabolism disorders and the abnormal hemorheology.

Key concepts: Hemorheology, Flavones, Hyperlipidemia, Internal medicine, Hematocrit, Blood lipids, Chemistry, Endocrinology

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Effects of flavones from Zea Mays L(ZMLF) on blood lipid and hemorheologic parameters in hyperlipemic rats — Research Paper | ScholarLens