Clinical observation of Bailemian Capsules combined with flupentixol and melitracen in treatment of senile coronary heart disease with anxiety symptoms

Objective To evaluate curative effect of Bailemian Capsules combined with flupentixol and melitracen in treatment of senile coronary heart disease with anxiety symptoms, and provide reference for clinic. Methods Patients(112 cases) of senile coronary heart disease with anxiety symptoms in Shaanxi Provincial Chinese Medicine Hospital from January 2011 to June 2014 were randomly divided into control group(56 cases) and treatment group(56 cases). Two groups were given conventional drug treatment of coronary heart disease. Patients in control group were po administered with Flupentixol and Melitracen Tablets, 1 tablet/time, twice daily. Patients in treatment group were po administered with Bailemian Capsules 4 capsules/time on the basis of control group, twice daily. The patients in two groups were treated for 14 d. After treatment, the efficacy was evaluated, and anxiety scores and changes of blood lipid in two groups were compared. Results After treatment, the efficacies in the control and treatment groups were 73.2% and 92.9%, respectively, and there were differences between two groups(P 0.05). After treatment, anxiety scores in two groups were obviously decreased, and the difference was statistically significant in the same group(P 0.05). The reducing degrees in treatment group were better than those in control group, with significant difference between two groups(P 0.05). After treatment, the levels of TG, TC, and LDL-C were significantly decreased(P 0.05), and the observed indexes in treatment group were better than those in control group, with significant difference between two groups(P 0.05). Conclusion Bailemian Capsules combined Flupentixol and Melitracen Tablets has clinical curative effect in treatment of senile coronary heart disease with anxiety symptoms, and can significantly improve the clinical symptoms, relieve anxiety, decrease the levels of blood lipid, and reduce adverse reactions, which has a certain clinical application value.