Analysis of drug resistance of bacteria isolated from patients in synthetic hospitals

Objective To analyze the resistant status of clinically isolated bacteria and provide scientific basis for guidance of clinical treatment in Guangzhou City. Methods Retrospective survey was made on the isolation of bacteria from clinical samples in the Affiliated Hospital of Guangdong Medical College from January 2003 to January 2005 and the results of drug sensitivity tests were analyzed. Results Among the 1 719 pathogenic bacteria isolated 563 strains were gram-positive bacteria with a positive rate of 32.8% and 1 156 strains were gram-negative bacteria accounted for 67.2%. Staphylococcus aureus was the predominated strains of gram positive bacterium and hemolytic streptococcus;while Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae were predominated. A lot of strains of gram-positive bacteria and gram-negative bacteria were strongly resistant to cephalosporin.Gram positive and gram negative bacteria were most sensitive to vancomycin and imipenem, respectively. Conclusion The resistance of local bacteria to antibiotics are serious and drug sensitivity tests be conducted to guide clinical use of drugs and delay the development of drug resistance.