Clinical and pathological analysis of solitary fibrous tumors

Objective To study the clinicopathologic characteristics and differential diagnosis of the solitary fibrous tumor(SFT).Methods Three cases of solitary fibrous tumour were analyzed by histological observation and immunohistochemical techniques.Results The tumor located in thoracic cavity and abdomen cavity respectively with 11.0cm×9.5cm×8.0cm to 10.0cm×10.5cm×7.2cm in size.Histologically,the tumor was composed of fibroblastic like spindle cells and bands of hyalinized collagen in varying proportions,arranged in fascicles and storiform pattern and some parts stroma showed hemangiopericytoma-like pattern and myxoid changes.Immunohistochemically,the tumor cells were positively reacted with CD34,Ⅴ imentin,CD99 and bcl-2,but nagathvely with CK,calretinin,MG,EMA,Des,SMA,S-100 protin,CD68 and CD117 in three cases.Conclusion SFP is a rare spindle cell tumor,and can be dignosed by histological and immunohistochemical findings.