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2000•Journal of Modern RehabilitationRequires access

Effect of tetrandrine on fibroblasts derived from hypertrophic scar

Li Wan

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Abstract

Objective: To observe the effects of tetrandrine on fibroblasts clerived from hypertrophic scar.Methods:To add different dilution of tetrandrine to fibroblast cultivating,then observe the change of proliferation and activity of dehydrogenase in mitochondrion of fibroblasts.Results:Tetrandrine can inhibit proliferation of cells and activity of dehydrogenase in mitochondrion.Conclusion:Because the predominant matrix component in hypertrophic scar is synthesized by fiobroblasts ,so tetrandrine may have a good effects on treating patients suffering from hypertrophic scar.

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What this paper is about

Objective: To observe the effects of tetrandrine on fibroblasts clerived from hypertrophic scar.Methods:To add different dilution of tetrandrine to fibroblast cultivating,then observe the change of proliferation and activity of dehydrogenase in mitochondrion of fibroblasts.Results:Tetrandrine can inhibit proliferation of cells and activity of dehydrogenase in mitochondrion.Conclusion:Because the predominant matrix component in hypertrophic scar is synthesized by fiobroblasts ,so tetrandrine may have a good effects on treating patients suffering from hypertrophic scar.

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Available abstract

Objective: To observe the effects of tetrandrine on fibroblasts clerived from hypertrophic scar.Methods:To add different dilution of tetrandrine to fibroblast cultivating,then observe the change of proliferation and activity of dehydrogenase in mitochondrion of fibroblasts.Results:Tetrandrine can inhibit proliferation of cells and activity of dehydrogenase in mitochondrion.Conclusion:Because the predominant matrix component in hypertrophic scar is synthesized by fiobroblasts ,so tetrandrine may have a good effects on treating patients suffering from hypertrophic scar.

Key concepts: Tetrandrine, Hypertrophic scar, Fibroblast, Mitochondrion, Chemistry, Molecular biology, Medicine, Biology

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