2001•Journal of Modern RehabilitationRequires access
Inhibition of tetrandrine on prolif eration of fibroblasts derived from hypertrophic scar
Yang Xin
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Abstract
Objective To observe the effects of tetrandrin e on proliferation of fibroblasts derived from hypertrophic scar.Method Cul-turing fibroblasts with different c oncentration solution of tetrandrine ,then observe the proliferative c apability by MTT,and its toxicity to the fibroblasts.Result Tetrandine can inhibit proliferati ve capability of fibroblasts derived from hypertrophic scar ,and has no t oxicity to it when concentration is below 80mg /L.Conclusion Because fibroblasts have the predom inant role in the hypertrophic scar,and tetrandrine can inhibit the proliferative capability of them,so it may have a good effect on the prevention and treatment of hypertrophic scar.