2014Chinese Journal of General PracticeRequires access

The applied research of stored autologous blood transfusion in heart valve replacement surgery

WU Xiao-ya

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Abstract

Objective To investigate the value of stored autologous blood transfusion in heart valve replacement surgery. Methods Study on 38 cases of heart valve replacement patients and stored autologous blood 200 to 600 ml before surgery. And then analysis of the experiment date change of the routine blood tests and blood coagulation before and after blood collection and also before and after taking autologous blood transfusion was conducted. And statistics of adverse reactions and saving blood was performed. Results There was no significantly difference in various blood indicators before and after blood collections( P 0. 05). And also there existed no significant changes in other indicators in addition to platelets, PT and APTT( P 0. 05). HB,HCT and RBC were lower than those before surgery( P 0. 01),but located within the normal reference range,did not cause tissue hypoxia,avoid homologous blood transfusion rate was 47. 37%( 18 /38); no adverse transfusion reactions occurred in all patients in the transfusion process. Conclusion Stored autologous blood transfusion was safe and effective,and can be a partial solution to heart valve replacement surgery transfusion requirements,which can reduce the amount of allogeneic blood transfusion,and it had good clinical value.

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What this paper is about

Objective To investigate the value of stored autologous blood transfusion in heart valve replacement surgery. Methods Study on 38 cases of heart valve replacement patients and stored autologous blood 200 to 600 ml before surgery. And then analysis of the experiment date change of the routine blood tests and blood coagulation before and after blood collection and also before and after taking autologous blood transfusion was conducted. And statistics of adverse reactions and saving blood was performed. Results There was no significantly difference in various blood indicators before and after blood collections( P 0. 05). And also there existed no significant changes in other indicators in addition to platelets, PT and APTT( P 0. 05). HB,HCT and RBC were lower than those before surgery( P 0. 01),but located within the normal reference range,did not cause tissue hypoxia,avoid homologous blood transfusion rate was 47. 37%( 18 /38); no adverse transfusion reactions occurred in all patients in the transfusion process. Conclusion Stored autologous blood transfusion was safe and effective,and can be a partial solution to heart valve replacement surgery transfusion requirements,which can reduce the amount of allogeneic blood transfusion,and it had good clinical value.

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Available abstract

Objective To investigate the value of stored autologous blood transfusion in heart valve replacement surgery. Methods Study on 38 cases of heart valve replacement patients and stored autologous blood 200 to 600 ml before surgery. And then analysis of the experiment date change of the routine blood tests and blood coagulation before and after blood collection and also before and after taking autologous blood transfusion was conducted. And statistics of adverse reactions and saving blood was performed. Results There was no significantly difference in various blood indicators before and after blood collections( P 0. 05). And also there existed no significant changes in other indicators in addition to platelets, PT and APTT( P 0. 05). HB,HCT and RBC were lower than those before surgery( P 0. 01),but located within the normal reference range,did not cause tissue hypoxia,avoid homologous blood transfusion rate was 47. 37%( 18 /38); no adverse transfusion reactions occurred in all patients in the transfusion process. Conclusion Stored autologous blood transfusion was safe and effective,and can be a partial solution to heart valve replacement surgery transfusion requirements,which can reduce the amount of allogeneic blood transfusion,and it had good clinical value.

Key concepts: Medicine, Autologous blood, Surgery, Blood transfusion, Blood conservation, Adverse effect, Platelet, Anesthesia

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