Clinical observation on ulcerative colitis treated by oral sulfasalazine and retention enema of Xianbaitang.

[Objective]To evaluate the clinical efficacy of Xianbaitang retention enema and sulfasalazine on ulcerative colitis.[Methods]Eighty patients with ulcerative colitis were divided randomly into 2 groups:30 patients were taken as control group treated with sulfasalazine oral and 50 patients were taken as enema group treated with traditional Chinese medicine enema and oral sulfasalazine.After two weeks treatment,defecation frequency,rectal bleeding,relief of abdominal pain in all patients were observed.Colonoscopy was performed.[Results]The remission time of clinical symptoms of enema group was shorter than that of control group(P0.01).The endoscopic relieving rate was 73.33% in control group and 96% in enema group(P0.01).The total effective rate was 92% in enema group and 73.33% in control group(P0.01).[Conclusion]Combination of sulfasalazine with Xianbaitang by retention enema has a high early remission rate for ulcerative colitis compared to the usage of sulfasalazine alone.