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Clinical study of nimodipine in preventing and treating cerebral vasospasm after subarachnoid hemorrhage

Zhu Yonghu

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Abstract

Objective To identify the effect of nimodipine in preventing and treating cerebral vasospasm(CVS) after subarachnoid hemorrhage(SAH).Methods 120 patients with SAH were randomly divided into case group(70 patients) and control group(50 patients).The patients of case group were accepted both routine therapy just as control group and nimodipine injection 10mg/50 ml,ivbydrip,then,nimodipine tablet 30mg,po.Results The morbidity of CVS and cerebral infarction(CI) and the endurable time of CVS following SAH and the mortality of SAH in the case group was significantly lower than that of the control group.The cure rate of CVS in the case group was obviously higher than that of the control group.The morbidity of rehemorrhage had no statistical difference between the two groups.Conclusion Nimodipine is an ideal therapy in preventing and treating CVS after SAH and there is no danger of rehemorrhage.

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What this paper is about

Objective To identify the effect of nimodipine in preventing and treating cerebral vasospasm(CVS) after subarachnoid hemorrhage(SAH).Methods 120 patients with SAH were randomly divided into case group(70 patients) and control group(50 patients).The patients of case group were accepted both routine therapy just as control group and nimodipine injection 10mg/50 ml,ivbydrip,then,nimodipine tablet 30mg,po.Results The morbidity of CVS and cerebral infarction(CI) and the endurable time of CVS following SAH and the mortality of SAH in the case group was significantly lower than that of the control group.The cure rate of CVS in the case group was obviously higher than that of the control group.The morbidity of rehemorrhage had no statistical difference between the two groups.Conclusion Nimodipine is an ideal therapy in preventing and treating CVS after SAH and there is no danger of rehemorrhage.

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Available abstract

Objective To identify the effect of nimodipine in preventing and treating cerebral vasospasm(CVS) after subarachnoid hemorrhage(SAH).Methods 120 patients with SAH were randomly divided into case group(70 patients) and control group(50 patients).The patients of case group were accepted both routine therapy just as control group and nimodipine injection 10mg/50 ml,ivbydrip,then,nimodipine tablet 30mg,po.Results The morbidity of CVS and cerebral infarction(CI) and the endurable time of CVS following SAH and the mortality of SAH in the case group was significantly lower than that of the control group.The cure rate of CVS in the case group was obviously higher than that of the control group.The morbidity of rehemorrhage had no statistical difference between the two groups.Conclusion Nimodipine is an ideal therapy in preventing and treating CVS after SAH and there is no danger of rehemorrhage.

Key concepts: Nimodipine, Medicine, Cerebral vasospasm, Subarachnoid hemorrhage, Anesthesia, Cerebral infarction, Vasospasm, Surgery

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