Study on Clinical Features and Renal Pathology in 62 Patients with IgA Nephropathy

Objective To investigate the relationship between clinical features and renal pathological classification in IgA nephropathy(IgAN).Methods Clinical features and renal pathological classification in 62 paients with IgAN were collected and analyzed.Results Mesangial proliferative glomerulonephtitis,focal proliferative glomerulonephritis and focal segmental glomerulosclerosis are the most common types(90.32%),Lee's pathological grade Ⅲ and Ⅳ are the most common types(82.26%).Blood pressure,serum creatinine,uric acid and 24-hour urinary protein levels increase with Lee's pathological grade increasing(P0.05 or P0.01).There is positive correlation between Katafuchi score and systolic blood pressure,serum creatinine,urea nitrogen,uric acid and 24-hour urinary protein levels(P0.01).Conclusion Renal pathology in IgAN is significantly correlated with clinical features.