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2012•Jiangsu Medical JournalRequires access

Pathological characteristics of 407 cases with IgA nephropathy

Bin Liu

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Abstract

Objective To analyze the pathological characteristics of IgA nephropathy(IgAN).Methods A positive diagnosis of primary IgAN was made after successive native renal biopsies in 407 in-patients.The pathological features of these patients were analyzed retrospectively.ResultsLee′s pathological grades of Ⅱ and Ⅲ were the most common types.Pathologically,focal segmental glomerulonephritis accounted for 38.04%,mesangial proliferative glomerulonephritis for 32.24% and minimal lesion for 24.28% in 407 patients with IgAN.Lee′s classification was correlated to the intensity of IgA deposition(Z=17.187,P0.05).Conclusion The pathological characteristics of IgAN are varied.There is a correlation between Lee′s classification and the intensity of IgA deposition in IgAN.

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What this paper is about

Objective To analyze the pathological characteristics of IgA nephropathy(IgAN).Methods A positive diagnosis of primary IgAN was made after successive native renal biopsies in 407 in-patients.The pathological features of these patients were analyzed retrospectively.ResultsLee′s pathological grades of Ⅱ and Ⅲ were the most common types.Pathologically,focal segmental glomerulonephritis accounted for 38.04%,mesangial proliferative glomerulonephritis for 32.24% and minimal lesion for 24.28% in 407 patients with IgAN.Lee′s classification was correlated to the intensity of IgA deposition(Z=17.187,P0.05).Conclusion The pathological characteristics of IgAN are varied.There is a correlation between Lee′s classification and the intensity of IgA deposition in IgAN.

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Available abstract

Objective To analyze the pathological characteristics of IgA nephropathy(IgAN).Methods A positive diagnosis of primary IgAN was made after successive native renal biopsies in 407 in-patients.The pathological features of these patients were analyzed retrospectively.ResultsLee′s pathological grades of Ⅱ and Ⅲ were the most common types.Pathologically,focal segmental glomerulonephritis accounted for 38.04%,mesangial proliferative glomerulonephritis for 32.24% and minimal lesion for 24.28% in 407 patients with IgAN.Lee′s classification was correlated to the intensity of IgA deposition(Z=17.187,P0.05).Conclusion The pathological characteristics of IgAN are varied.There is a correlation between Lee′s classification and the intensity of IgA deposition in IgAN.

Key concepts: Pathological, Nephropathy, Glomerulonephritis, Medicine, Mesangial proliferative glomerulonephritis, Pathology, Immunoglobulin A, Lesion

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